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The Centre for Functional Genomics at Oxford Brookes University uses state-of-the-art methods to decipher how genes control life and how genetic changes cause differences between organisms. Recent years have brought great progress in sequencing techniques and research methods in the area of genomics. Hence, the three Research Groups associated with the Centre explore different next generation sequencing approaches to understand the genomic and genetic principles that govern biological form and function.
In addition to the focus on their own research themes, members of the Centre also provide services in the areas of sequencing data analysis and project design for external and internal collaborators. They are also involved in student teaching and offer short courses and training opportunities in cutting-edge methods for sequencing data analysis.
Saad Arif's research interests are Ecological and Evolutionary Genomics.
Korneel Hens maps gene regulatory networks that regulate cell fate maintenance and nutritional homeostasis in adult organisms.
Sebastian Kittelmann studies the role of enhancers in evolution and development and how enhancer sequence variation translates into functional differences.
The Centre for Functional Genomics offers courses to external and internal researchers who want to learn about sequencing data analysis techniques. The following courses are planned:
Day 1 and 2 will be workshops on generic computational skills for biologists who have little to no experience in R and/or the Linux environment and would like to gain further skills in these areas. Day 3 will be end-to-end tutorials on analyzing RNAseq and ATAC-seq (or ChIP-seq) data
Our Eco-Evo-Devo Summer School builds on the successful courses we ran in 2012, 2014, 216 and 2018 to again provide postgraduates with the opportunity to explore key questions and experimental approaches in ecological evolutionary
developmental biology with leading scientists in this field.
I have generated sequencing data. What next?
Sequencing techniques are being used by researchers working in all kinds of different fields to answer very different questions. However, it is not always clear to every scientist what their data can be used for. The Centre for Functional Genomics provides three different kinds of services to help.
Often scientists are unsure how they can use sequencing technologies to help them answer their specific question. We can help with project design and planning, especially for next generation sequencing projects (e.g. RNAseq or ChIP-seq). This should be done as early in the project planning as possible, since a successful grant application depends on a convincing research strategy.
In cases where scientists have already generated sequencing data but have no trained personnel to analyse them, we can provide this service. Also the re-analysis of published datasets for a different purpose or the comparison of different datasets can be done. We offer to either analyse datsets ourselves or to train other researchers in data analysis in a one-to-one fashion.
The analysis of large datasets requires high computational power in order to be fast and efficient.We have high spec computers in the Centre that can be used also remotely by other researchers at Oxford Brookes University to conduct genomics data analysis.
If you have any questions please don't hesitate to get in touch, contact us via email