Department of Biological and Medical Sciences

Study Participation

  • Our research would not be possible without the participation of families affected by anophthalmia, microphthalmia, coloboma and other eye development disorders. These families have been recruited into our study ‘ The genetics of Eye and Brain Anomalies’, which has been ongoing since 1999 and now includes over 400 families. This national study has been fully approved by the Cambridge East Ethics Committee.

    We are continuing to recruit new families into this study and are welcoming any interest. Our study focuses on families affected by anophthalmia, microphthalmia, coloboma and anterior segment anomalies including Peters anomaly and Rieger syndrome. Participation involves a one-off visit to Professor Nicky Ragge’s clinic (which are held through the NHS in Birmingham or Rugby, and on a research basis in Oxford), during which family members will receive an eye and general examination and may be asked to give a blood sample.

    Participants will be updated about the research, and will be asked to visit again when the research team has significant findings relating to their eye anomaly.

    If you have any questions about this study, or if you are considering to participate you can contact us through or call us on 01865 484413 or from abroad +44 1865 484413.