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We recently published a report of a family with an unusual language ability; they can voluntarily speak backwards. Genetic sequencing revealed a rare change in the genetic sequence that was only found in family members with the ability to speak backwards (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738289/). We are characterising the effects of this coding change upon protein function to try to link the change at the genetic sequence to a neurological mechanism that might explain their exceptional memory. We are looking for additional individuals who can speak backwards.
Research Question: Do changes in RIC3 function contribute to better working memory?
This project is in collaboration with researchers at KU Leuven, University of Novi Sad, University of Belgrade, University of Szeged, Oncology Institute of Vojvodina and with the Bermudez-Diaz lab at Brookes.
This research is funded by a Leverhulme project grant. It has previously been funded by the MRC and by a Research Excellence Award from Brookes University.