Department of Biological and Medical Sciences


  • Research Articles

    Schönauer, A., Paese, C. L., Hilbrant, M., Leite, D. J., Schwager, E. E., Feitosa, N. M., Eibner, C., Damen, W. G. and McGregor A. P. (2016). The Wnt and Delta-Notch signalling pathways interact to direct pair-rule gene expression via caudal during segment addition in the spider Parasteatoda tepidariorumDevelopment 143, 2455-63.

    Leite, D. J., Ninova, M., Hilbrant, M., Arif, S., Griffiths-Jones S., Ronshaugen M., and McGregor, A. P. (2016). Pervasive microRNA duplication in chelicerates: insights from the embryonic microRNA repertoire of the spider Parasteatoda tepidariorumGenome Biology and Evolution, 8, 2133-44.

    Torres-Oliva, M., Almudi, I., McGregor, A. P. and Posnien, N. (2016). A robust (re-) annotation approach to generate unbiased mapping references for RNA-seq-based analyses of differential expression across closely related species. BMC Genomics 17, 392.

    Crocker, J., Abe, N., Rinaldi, L., McGregor, A. P., Frankel, N., Wang, S., Alsawadi, A., Valenti, P., Plaza, S., Payre, F., Mann, R. S. and Stern, D. L. (2015). Low affinity binding site clusters confer hox specificity and regulatory robustness. Cell 160, 191-203.

    Janssen, R.,* Schönauer, A.,* Weber, M., Turetzek, N., Hogvall, M., Goss, G. E., Patel, N. H., McGregor, A. P. and Hilbrant, M. (2015). The evolution and expression of panarthropod frizzled genes. Frontiers in Ecology and Evolution 3, 96. *Contributed equally.

    Tanaka, K. M., Hopfen, C., Herbert, M. R., Schlötterer, C., Stern, D. L., Masly, J. P., McGregor, A. P. and Nunes, M. D. S. (2015). Genetic architecture and functional characterization of genes underlying the rapid diversification of male external genitalia between Drosophila simulans and Drosophila mauritiana. Genetics 200, 357-369.

    Hilbrant, M., Almudi, I., Leite, D. J.,  Kuncheria, L., Posnien, N., Nunes, M. D. S. and McGregor, A. P. (2014). Sexual dimorphism and natural variation within and among species in the Drosophila retinal mosaic. BMC Evolutionary Biology 14, 240.

    Posnien, N., Zeng, V., Schwager, E. E., Pechmann, M., Hilbrant, M., Keefe, J. D., Damen, W. G. M., Prpic-Schäper, N., McGregor, A. P., and Extavour, C. G. (2014). A comprehensive reference transcriptome resource for the common house spider Parasteatoda tepidariorum. PLoS ONE 9, e104885.

    Hogvall, M., Schönauer, A., Budd, G. E., McGregor, A. P., Posnien, N. and Janssen, R. (2014). Analysis of the Wnt gene repertoire in an onychophoran provides new insights into the evolution of segmentation. EvoDevo 5, 14.

    Arif, S., Murat, S., Almudi, I., Nunes, M. D. S., Bortolamiol-Becet, D., McGregor, N. S., Currie, J. M. S., Hughes, H., Ronshaugen, M., Sucena, E., Lai, E. C., Schlötterer, C. and McGregor, A. P. (2013). Evolution of mir-92a underlies natural morphological variation in Drosophila melanogaster. Current Biology 23, 523-528.

    Arif, S., Hilbrant, M., Hopfen, C., Almudi, I., Nunes, M. D. S., Posnien, N., Kuncheria, L., Tanaka, K., Mitteröcker, P., Schlötterer, C. and McGregor, A. P. (2013). Genetic analysis of differences in eye and face morphology between Drosophila simulans and Drosophila mauritiana. Evolution and Development 15, 257-267.

    Posnien, N., Hopfen, C., Hilbrant, M., Ramos-Womack, M., Murat, S., Schönauer, A., Herbert, S. L., Nunes, M. D. S., Arif, S., Breuker, C. J., Schlötterer, C., Mitteroecker, P. and McGregor, A. P. (2012). Evolution of eye morphology and rhodopsin expression in the Drosophila melanogaster species subgroup. PLoS One 7, e37346.

    Pechmann, M., Khadjeh, S., Turetzek, N., McGregor, A. P., Damen, W. G. M. and Prpic, N-M. (2011). Novel Function of distal-less as a gap gene during spider segmentation. PLoS Genetics 7, e1002342

    Frankel, N., Erezyilmaz, D. F., McGregor, A. P., Wang, S., Payre, F. and Stern, D. L. (2011). Multiple small-effect mutations underlie evolutionary divergence of a modular enhancer. Nature 474, 598-603.

    Janssen, R., Le Gouar, M., Pechmann, M., Poulin, F., Bolognesi, R., Schwager, E. E., Hopfen, C., Colbourne, J. K., Budd, G. E., Brown, S. J., Prpic, N. M., Kosiol, C., Vervoort, M., Damen, W. G. M., Balavoine, G. and McGregor, A. P. (2010). Conservation, loss, and redeployment of Wnt ligands in protostomes: implications for understanding the evolution of segment formation. BMC Evolutionary Biology 10, 374.

    The International Aphid Genomics Consortium (2010). Genome sequence of the pea aphid Acyrthosiphon pisumPLoS Biology 23, 8.

    Shigenobu, S., Bickel, R. D., Brisson, J. A., Butts, T., Chang, C., Christiaens, O., Davis, G. K., Duncan, E. J., Ferrier, D. E. K., Iga, M., Janssen, R., Lin, G., Lu, H., McGregor, A. P., Miura, T., Smagghe, G., Smith, J. M., van der Zee, M., Velarde, R., Wilson, M. J., Dearden, P. K. and Stern, D. L. (2010). Comprehensive survey of developmental genes in the pea aphid, Acyrthosiphon pisum: frequent lineage-specific duplications and losses of developmental genes. Insect Molecular Biology 19, 47-62.

    Schwager, E. E., Pechmann, M., Feitosa, N. M., McGregor, A. P. and Damen, W. G. M. (2009). hunchback functions as a segmentation gene in the spider Achaearanea tepidariorum. Current Biology 19, 1333-1340.

    Pechmann, M., McGregor. A. P., Schwager, E. E., Feitosa, N. M. and Damen. W. G. M. (2009). Dynamic gene expression is required for anterior regionalization in a spider. Proceedings of the National Academy of Sciences USA 106, 1468-1472.

    McGregor, A. P., Pechmann, M., Schwager, E. E., Feitosa, N. M., Kruck, S., Aranda, M. and Damen, W. G. M. (2008). Wnt8 is required for establishment of the growth zone and development of opisthosomal segments in a spider. Current Biology 18, 1619-1623. 

    Hermisson, J. and McGregor, A. P. (2008). Pleiotropic scaling and QTL data. Nature 456, E3-E4.

    Gregor, T., McGregor, A. P. and Wieschaus, E. F. (2008). Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos. Developmental Biology 316, 350-358. 

    Gregor, T., Wieschaus, E. F., McGregor, A. P., Bialek, W. and Tank, D. W. (2007). Stability and nuclear dynamics of the Bicoid morphogen gradient. Cell 130, 141-152.

    McGregor, A. P., Orgogozo, V., Delon, I., Zanet, J., Srinivasan, D. G., Payre, F. and Stern, D. L. (2007). Morphological evolution through multiple cis-regulatory mutations at a single gene. Nature 448, 587-590.

    Wratten, N. S., McGregor, A. P., Shaw, P. J. and Dover, G. A. (2006). Evolutionary and functional analysis of the tailless enhancer in Musca domestica and Drosophila melanogasterEvolution and Development 8, 6-15.

    Shaw, P. J., Wratten, N. S., McGregor, A. P. and Dover, G. A. (2002). Co-evolution in bicoid- dependent promoters and the inception of regulatory incompatibilities among species of higher Diptera. Evolution and Development 4, 265-277.

    McGregor, A. P., Shaw, P. J. and Dover, G. A. (2001). Sequence and expression of the hunchback gene in Lucilia sericata: a comparison with other Dipterans. Development, Genes and Evolution 211, 315-318.

    McGregor, A. P., Shaw, P. J., Hancock, J. M., Bopp, D., Hediger, M., Wratten, N. S. and Dover, G. A. (2001). Rapid restructuring of bicoid-dependent hunchback promoters within and between Dipteran species: implications for molecular co-evolution. Evolution and Development 3, 397-407.

    Shaw, P. J., Salameh, A., McGregor, A. P., Bala, S. and Dover, G. A. (2001). Divergent structure and function of the bicoid gene in Muscoidea fly species. Evolution and Development 3, 251-262. 

    Review Articles

    Buffry, A. D., Mendes, C. C. and McGregor, A. P. (2016). The functionality and evolution of eukaryotic transcriptional enhancers. Advances in Genetics 96, 143-206.

    Leite, D. J. and McGregor, A. P. (2016). Arthropod evolution and development: recent insights from chelicerates and myriapods. Current Opinion in Genetics and Development 39 93-100.

    Arif, S.*, Kittelmann, S.* and McGregor, A. P. (2015). From shavenbaby to the naked valley: trichome formation as a model for evolutionary developmental biology. Evolution and Development 17, 120-126. *Contributed equally.

    Nunes, M. D. S., Arif, S., Schlötterer, C. and McGregor, A. P. (2013). A Perspective on Micro-Evo-Devo: Progress and Potential. Genetics 195, 625-634.

    Hilbrant, M., Damen, W. G. M. and McGregor, A. P. (2012). Evolutionary crossroads in developmental biology: the spider Parasteatoda tepidariorumDevelopment 139, 2655-2662.

    Murat, S., Hopfen, C. and McGregor, A. P. (2010). The function and evolution of Wnt genes in arthropods. Arthropod Structure and Development 39, 446-452.

    McGregor, A. P., Pechmann, M., Schwager, E. E. and Damen. W. G. M. (2009). An ancestral regulatory network for posterior development in arthropods. Communicative and Integrative Biology 2, 174-176.

    McGregor, A. P., Hilbrant, M., Pechmann, M., Schwager, E. E., Prpic, N. M. and Damen, W. G. (2008). Cupiennius salei and Achaearanea tepidariorum: Spider models for investigating evolution and development. Bioessays 30, 487-498.

    McGregor, A. P. (2006). Wasps, beetles and the beginning of the ends. Bioessays 28, 683-686.

    McGregor, A. P. (2005). How to get ahead: the origin, evolution and function of bicoidBioessays 27, 904-913.

    Book Chapters

    Schwager, E. E., Schönauer, A., Leite, D. J., Sharma, P. P. and McGregor, A. P. (2015). Chelicerata. In: Evolutionary Developmental Biology of Invertebrates, ed Wanninger A (Spinger, Berlin).