Department of Biological and Medical Sciences

About

  • Research conducted by the Membrane Transport Research Group is aimed at understanding the structure-functional relationship of membrane transport proteins, especially for transporters involved in the uptake and delivery of nutrients across cell membranes such as those of intestinal enterocytes and renal proximal tubule absorptive epithelial cells. This is of great interest, not least to the pharmaceutical industry as these transporters are potential routes for drug delivery and absorption.

    We use a combination of molecular biology and protein biochemistry techniques, including in vitro protein expression, to study the structure-functional relationship of the transporters at a molecular level. In parallel with input from medicinal chemistry colleagues who synthesize novel compounds, allowing us to develop and test novel peptide-conjugated progrugs in our in vitro systems.