I am a post-doctoral research assistant working in the plant endomembrane group at Oxford Brookes University.
My research is focused on developing image analysis methods that enable quantification of the plant endoplasmic reticulum (ER) and identification of novel ER shaping proteins. Of particular interest is the Lunapark protein family which play a key role in maintaining proper ER structure and contains the first known cisternae specific marker. I have a strong focus on image analysis and advanced microscopy techniques.
Projects as Principal Investigator, or Lead Academic if project is led by another Institution
- How to build a protein factory: linking structure and function of the plant ER (01/12/2022 - 30/11/2025), funded by: Leverhulme Trust, funding amount received by Brookes: £111,881
Spatola Rossi T, Pain C, Botchway SW, Kriechbaumer V, 'FRET-FLIM to determine protein interactions and membrane topology of enzyme complexes'
Current Protocols in Plant Biology 2 (2022)
ISSN: 2379-8068 eISSN: 2379-8068Abstract Published here Open Access on RADAR
McGinness AJ, Schoberer J, Pain C, Brandizzi F, Kriechbaumer V, 'On the nature of the plant ER exit sites'
Frontiers in Plant Science 13 (2022)
ISSN: 1664-462X eISSN: 1664-462XAbstract Published here Open Access on RADAR
Pain C, Tolmie F, Wojcik S, Wang P, Kriechbaumer V, 'intER-ACTINg: the structure and dynamics of ER and actin are interlinked'
Journal of Microscopy [online first] (2022)
ISSN: 0022-2720 eISSN: 1365-2818Abstract Published here Open Access on RADAR
Cosma M-A, Curtis NL, Pain C, Kriechbaumer V, Bolanos-Garcia VM, 'Biochemical, biophysical, and functional characterisation of the E3 Ubiquitin ligase APC/C regulator CDC20 from Arabidopsis thaliana'
Frontiers in Physiology Online first (2022)
ISSN: 1664-042X eISSN: 1664-042XAbstract Published here
Kerselidou D, Dohai BS, Nelson DR, Daakour S, De Cock N, Al Oula Hassoun Z, Kim D-K, Olivet J, El Assal DC , Jaiswal A, Alzahmi A, Saha D, Pain C, Matthijssens F, Lemaitre P, Herfs M, Chapuis J, Ghesquiere B, Vertommen D, Kriechbaumer V, Knoops K, Lopez-Iglesias C, van Zandvoort M, Lambert J-C, Hanson J, Desmet C ,Thiry M, Lauersen K, Vidal M, Van Vlierberghe P, Dequiedt F, Salehi-Ashtiani K, Twizere J-C, 'Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells'
Science Advances 7 (19) (2021)
ISSN: 2375-2548 eISSN: 2375-2548Abstract Published here Open Access on RADAR
Zang J, Klemm S, Pain C, Duckney P, Bao Z, Stamm G, Kriechbaumer V, Bürstenbinder K, Hussey PJ, Wang P, 'A novel plant actin-microtubule bridging complex regulates cytoskeletal and ER structure at Endoplasmic Reticulum-Plasma Membrane Contact Sites (EPCS) '
Current Biology 31 (6) (2021) pp.1251-1260
ISSN: 0960-9822Abstract Published here Open Access on RADAR
Pain C, Kriechbaumer V, 'Defining the dance: quantification and classification of ER dynamics'
Journal of Experimental Botany 71 (6) (2019) pp.1757-1762
ISSN: 0022-0957 eISSN: 1460-2431Abstract Published here Open Access on RADAR