Following the completion of my doctorate in molecular virology at Oxford University in 1985, my research has focused on various aspects of insect virology with particular emphasis on baculovirus expression systems. I have published more than 90 papers in peer-reviewed journals, reviews and book chapters, and until recently was Insect Virus Editor for The Journal of General Virology. I have spoken at numerous national and international meetings, including The American Society for Virology, The Society for Invertebrate Pathology, Peptalk, Global Protein Summit and Baculovirus Technology.
I also played an integral role in the establishment of Oxford Expression Technologies (OET), trading under Oxford Brookes Enterprises Ltd, in 1997 and continue to work as Director and Chair of SAB.
The biology and replication of insect baculoviruses in cultured insect cells and in larvae, with a focus on the role of non-essential genes encoding proteins such as P10. chitinase and cathepsin, and the trafficking of virus proteins and particles through insect cells using a range of bioimaging techniques. We are also interested in the exploitation of baculoviruses as gene expression vectors that has led to patenting of a new platform technology ‘flashBAC’ for the production of recombinant viruses and the formation of spin-off company Oxford Expression Technologies Ltd.