Dr Andrew Jones

BSc, PhD

Senior Lecturer in Molecular Biology and Genomics

Department of Biological and Medical Sciences

Andrew Jones

Role

I completed my Biochemistry undergraduate degree at Imperial College London in 1996. I was then awarded a PhD at the University of Leeds in 2000, studying acetylcholinesterase and nicotinic acetylcholine receptors of the blood fluke, Schistosoma. In 2001 I carried on research of invertebrate cys-loop ligand-gated ion channels at the MRC Functional Genomics Unit, Oxford, until 2011. After a year's postdoctoral research at the Botnar Institute, Oxford, I became Senior Lecturer in Molecular Biology and Genomics at Oxford Brookes University in 2012.

Teaching and supervision

Modules taught

  • (Undergrduate) Scientific Skills
  • (Undergrduate) Professional and Experimental Skills
  • (Undergrduate) Molecular Biology (Module leader)
  • (Undergrduate) Independent Studies in Life Sciences
  • (Undergrduate) Project (Module leader)
  • (Masters) Advanced Molecular Techniques (Module leader)
  • (Masters) Genome Science
  • (Masters) Research Project

Supervision

PhDs completed:

Joseph Hawkins, 2015-2019, "The characterisation of bee nicotinic acetylcholine receptors".

Research

My laboratory is interested in gene diversity and the resulting functional/pharmacological properties of ligand-gated ion channels, using genome sequence analysis, molecular biology and electrophysiology. In particular, I am focusing on cys-loop ligand-gated ion channels of insects. The cys-loop ligand-gated ion channel superfamily includes nicotinic acetylcholine receptors, GABA receptors and glutamate-gated chloride channels, which play key roles in signalling and are also of interest as they are targets of pesticides. I am also interested in investigating changes (commonly mutations) in cys-loop ligand-gated ion channels that give rise to pesticide resistance.

Research group membership

REF Group: UoA5: Biomedicine, Cell and Developmental Biology, Ecology and Evolution, Genetics and Genomics

Lab Members

  • Dr Andrew Jones, Research Group Leader
  • Eleanor Mitchell, PhD Student
  • Jay Hands, PhD Student, joint supervision with Dr Casper Breuker

Research grants and awards

  • BBSRC Oxford Doctoral Training Program iCASE studentship 2018-2022
  • Oxford Brookes Research Excellence Award 2017
  • Nigel Groome PhD Studentship 2015-2018
  • Higher Education Innovation Funding (HEIF), Oxford Brookes University, 2014
  • The Leverhulme Trust RPG-2012-602: 'Characterising the functional spectrum of the mosquito GABA receptor'.

Projects as Principal Investigator, or Lead Academic if project is led by another Institution

  • Using spider venoms to develop novel, safer, insecticides for crop protection - Case studentship (01/09/2022 - 31/08/2026), funded by: Biotechnology & Biological Sciences Research Council (BBSRC), funding amount received by Brookes: £105,988
  • Oxford BBSRC DTP 21-22 (01/09/2021 - 31/08/2025), funded by: Biotechnology & Biological Sciences Research Council (BBSRC), funding amount received by Brookes: £129,284

Publications

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Further details

Press, publicity and reviews

Undergraduate project students in the laboratory of Andrew Jones are analysing mosquito DNA to determine the extent of insecticide resistance in Laos PDR, where Dengue fever and malaria are important health concerns: see the article Mosquito DNA study offers crucial clues to disease control in Laos.

Further information

ResearchGate: https://www.researchgate.net/profile/Andrew_Jones26

Google Scholar: https://scholar.google.co.uk/citations?hl=en&user=rWhzuN8AAAAJ