• Oxford Brookes Bioimaging Unit

  • Oxford Brookes Bioimaging Unit (OBBU) is a core facility based in the Faculty of Health and Life Sciences. Our unit has a wide range of light and electron microscopes, as well as fully-equipped electron microscopy sample preparation labs. We also have dedicated workstations for 3D image analysis. Our expertise lies in high-resolution live cell imaging and 3D electron microscopy.

  • Light Microscopy

    Zeiss LSM 800 with Airyscan

    Zeiss LSM 800 with Airyscan

    Confocal laser scanning microscopy is conducted on our Zeiss LSM 510 Meta.

    Zeiss LSM 880 with Airyscan

    Zeiss LSM 880 with Airyscan

    This equipment is currently not available to external users but will be in the future.

    Zeiss axioplan and others

    Zeiss axioplan and others

    Zeiss axioplan fluorescence microscope and other additional microscopes with digital imaging capability.

  • Electron Microscopy

    Electron Microsopes

    Zeiss Merlin VP compact with Gatan 3View2XP

    Zeiss Merlin VP compact with Gatan 3View2XP

    Zeiss Merlin compact VP with Gemini column. Field emission scanning electron microscope. Fitted with Gatan 3View system for serial block face scanning electron microscopy.

    Hitachi H-7650 TEM

    Jeol JEM-1400Flash

    Jeol JEM-1400Flash transmission electron microscope, with a Gatan OneView 16 Megapixel camera. Reaches an accelerating voltage of up to 120kV, for normal TEM imaging and electron tomography (using SerialEM).

    Hitachi S-3400N

    Hitachi S-3400N

    Hitachi S-3400N scanning electron microscope. Variable pressure mode is available.

    Specimen preparation equipment

    RMC Powertome PTPC and MT990 microtome

    RMC Powertome PTPC and MT990 microtome

    RMC Powertomes are available for producing ultrathin sections for TEM. Cryoultramicrotomy is also possible. The MT990 is available for histological sections. RMC knifemaker is used for glass knife making and is also situated in the microtomy suite.

    Baltec HMP 010 high pressure freezer

    Baltec HMP 010 high pressure freezer

    The HPM 010  high pressure freezer is available for rapid freezing of biological samples.

    RMC FS-8500

    RMC FS-8500

    The FS-8500 system is available for freeze substitution of frozen samples.

    Polaron Critical Point Dryer E3000

    Polaron Critical Point Dryer E3000

    Critical point dryer for SEM sample preparation.

    Agar scientific carbon coater

    Agar scientific carbon coater

    Carbon coater unit with plasma cleaning and glow discharge.

    Agar scientific sputter coater

    Agar scientific sputter coater

    Gold sputter coating for routine SEM sample preparation.