Biological Sciences (Human Biosciences)

In this module, you’ll learn essential training in professional career management skills, designed to assist you in actively planning and preparing for your future career. You’ll explore a career development cycle, starting with discovering your potential, considering opportunities within job roles, postgraduate study or training.

On completion of this module you’ll feel confident about competing in the graduate job market, whether you are applying for work placements or graduate jobs. You can expect to get hands-on with practical involvement from the university’s Career Consultants and employers.

After completion of this module you should have a clearer idea of where your career values lie, and a greater understanding of how you may realise your career aspirations.

In this module you’ll focus on the functional aspects of cells, molecules, tissues and organs at a whole-body level, and how these concepts can be applied to human health and disease.

Your study will focus on systems physiology, respiratory systems, cardiovascular, renal, endocrine, and autonomic nervous systems. You’ll discover how these systems can behave in an integrated and interdependent way.

Did you know that blood pressure is regulated by both the cardiovascular system and the kidneys, and blood pH by both the lungs and the kidneys?

In this insightful module, you’ll explore the mechanisms by which these individual systems are integrated and the response to any physiological disturbance. On completion of this module, you’ll have a greater understanding of how integrated physiology supports biotech, agriculture and medicine.

A study of structure and function of prokaryotic and eukaryotic genomes at the molecular level with an overview on the experimental evidence that has contributed to current concepts, models and paradigms and practical experience of key molecular biology laboratory techniques. The module focuses on both biomedical and environmental applications of modern molecular tools, with emphasis on phylogeny to complement 'Genetics'.

Want to make your stamp on eradicating some of the world’s major diseases? In this module you’ll discover how the biochemistry of eukaryotic cells plays an intrinsic role in the function of cell biology, with a special focus on mammalian tissues. You’ll be introduced to a number of key experimental procedures and laboratory techniques which will enable you to explore the chemical nature of the compounds in these highly fascinating cells, enlightening your knowledge on cellular processes.

You’ll develop an in-depth understanding of the biochemical events that occur when these cellular processes fail and give rise to diseases. You’ll also deepen your knowledge on both a cellular and systemic level, and absorb yourself within the enthralling biomedical diagnostic techniques delivered by leading experts in the field, equipping you with vital skills for the world of work.

You’ll learn to turn biological data into meaningful information in this module. Interpretation of data in the biological science world is more important than ever, and bioinformatics is an increasingly integral part of modern biological research. As part of your study, you’ll be introduced to computational thinking in biological sciences, enabling you to analyse, interpret, visualise and present data sets.

You’ll use your programming skills to tailor bespoke solutions to biological problems, make new discoveries, develop capacity for considering data-driven results, and reveal new insights from your findings. You’ll be introduced to the two most important molecules in cell biology, RNA and DNA, from a bioinformatics perspective.

On completion of this module, you’ll be well placed to forge a career with excellent employment prospects within life sciences, biotechnology, or the pharmaceutical industry.

How does food play an important role in our lives? Explore this question and more on this module. Throughout your studies, you’ll discover the societal and biological nutritional links from disease prevention, maintenance and therapeutic perspectives. You’ll enjoy weekly lectures that build upon and apply the knowledge gained during Nutrition Biochemistry and Metabolism (NUTR5004) in the previous semester.

Your learning journey will take you beyond the lecture room, introducing you to cutting-edge laboratory-based class techniques using specialist dietary analysis software, and preparing you for the career world. You’ll explore three broad sections: Nutrigenomics; which focuses on the role of gene expression and the genetic susceptibility to disease stages, chronic diseases, and specialist topics such as vegetarianism and alcohol.

In this module, you’ll learn how to manage ‘big data’ and machine learning techniques for drawing meaningful Biological Science conclusions.

You’ll get interactive and hands-on with the fundamentals of programming and analysis across biological, statistical and computer science elements. In addition, you’ll get up to speed on managing and communicating data from diverse biological disciplines using the R language for statistical computing.

On completion of this module you’ll gain highly transferable skills from across a range of disciplines, making you an asset for both research and employment.

You'll unravel key research ideas that are helping today’s biologists solve some of the world’s biggest biology questions. The fundamental concept of cell biology is the understanding of how organisms develop and how they interact and respond to their environment.

You’ll investigate molecular cell structures from animals, plants and fungi through a combination of practical experimental laboratory techniques and theoretical research. You'll be introduced to fascinating established methods such as fluorescent microscopy of living cells.

You’ll explore recent advances in cell biology such as novel treatments and therapies for diseases, cell processes such as cell division, and the impact of the environment on biological systems. You’ll also take a closer look at the composition of a cell – its’ components and intrinsic functions. By the end of this module, you'll have an excellent grasp of cell biology, which will allow you to progress to more advanced and specialised topics.

How are our genes passed from one generation to the next? How does DNA play a role in our genetic makeup? And what is the science behind evolution on earth? All these questions and more will be answered in this encapsulating module exploring the field of genetics.

You’ll gain specialist knowledge on real-world biomedical applications and computational analyses techniques, which will provide the perfect foundation to your further studies. You’ll benefit from gaining specialist knowledge from experts in the field. Whether it’s healthcare, endangered species, or cancer research, as a graduate you can expect your skills to make a lasting impact on society.

In this module you’ll be introduced to the theoretical background behind metabolic energy and human metabolism. You’ll learn about nutritional biochemistry in foods and how excessive consumption or suboptimal intake can impact internal biological mechanisms at a molecular, cellular and whole-body level.

This module serves as a precursor to NUTR5008 Applied Human Nutrition, where you’ll also gain an informative insight into the role of energy and nutrients in the various stages of the life cycle and their associations with chronic disease risk.

Once you graduate you can expect to be equipped for careers in public health, clinical nutrition/dietetics, or the food industry to name a few.

You can extend your course by taking a sandwich year in a relevant professional role, during which you’ll remain registered as a student. We’ll support your continued academic development in the workplace (e.g. a research, pharmaceutical or hospital laboratory). You’ll gain insight from working in a professional setting and develop new practical and career skills, whilst contributing to the work of the professional team hosting you. You’ll organise the placement yourself, with our help and advice, e.g. by applying for advertised placements or finding suitable hosts.

You’ll need to fund associated expenses during your sandwich year, usually your placement will be salaried. For a career as an NHS Biomedical Scientist, as well as your BSc Hons in Biomedical Science, you must register with the Health and Care Professions Council via an Institute of Biomedical Science (IBMS) Certificate of Competence Registration Portfolio. A placement in an IBMS laboratory can give you this opportunity.

This is the culmination of your degree, and your chance to delve into the world of research to pioneer your own breakthrough. As part of this module you’ll have the opportunity to create an individual piece of research related to your degree subject, working alongside a supervisor from the Department of Biological Sciences at Oxford Brookes University. You’ll be encouraged to explore opportunities to develop your project outside of the University, under the guidance of your tutor. You’ll participate in formal sessions that are designed to help you consider possible project choices and provide you with the necessary knowledge to search for outside project opportunities.

You’ll focus on the development of your professional skills and personalise your career ambitions. You’ll select your study elements, which will allow you flexibility and draw upon your research expertise and links with external partners. Some of the wide range of topics you’ll cover will be relevant to your degree, such as advanced microscopy, protein biochemistry, species identification, geographic information systems, entrepreneurship or science communication.

You’ll gain hands-on experience on how to competently perform techniques, and you’ll hear from professionals working in the sector, who will provide an insight into their career. You will learn how you can make a difference in the world and existing job market with the new knowledge and skills you’ll gain. Self-reflection is encouraged on this module, and you’ll get the chance to demonstrate your learning through a written report, talk, poster, leaflet, protocol, or oral viva.

You can extend your course by taking a sandwich year in a relevant professional role, during which you’ll remain registered as a student. We’ll support your continued academic development in the workplace (e.g. a research, pharmaceutical or hospital laboratory). You’ll gain insight from working in a professional setting and develop new practical and career skills, whilst contributing to the work of the professional team hosting you. You’ll organise the placement yourself, with our help and advice, e.g. by applying for advertised placements or finding suitable hosts.

You’ll need to fund associated expenses during your sandwich year, usually your placement will be salaried. For a career as an NHS Biomedical Scientist, as well as your BSc Hons in Biomedical Science, you must register with the Health and Care Professions Council via an Institute of Biomedical Science (IBMS) Certificate of Competence Registration Portfolio. A placement in an IBMS laboratory can give you this opportunity.

Neuroscience examines the brain, which is responsible for our entire nervous system; including how we process formation which influences how we feel, behave and remember things. This module will give you a fascinating insight into the latest major research fields in neuroscience. At the beginning of the course, you’ll review the structure and function of the neurone, explore human neuroanatomy and the development of the vertebrate nervous system.

As you delve deeper, you’ll then focus on the development of the brain, and how neural systems give rise to sensory perception, learning and memory, speech and language, motor control, vision, sleep-wake cycling and circadian rhythm. You will have the opportunity to develop and carry out your own in-depth study on a particular interest in neuroscience research, which will be assessed by a series of case studies and a reflective journal based on a visit to Oxford University / OUH clinical neuropathology.

You’ll gain a detailed insight of nutrition-based theory and practice within a clinical setting. You’ll investigate the processes behind approaches to clinical nutrition and explore the general principles that underlie most clinical cases. Your study will touch on human energy requirements during health, disease states, the management of nutrition-related diseases, and the uses of clinical dietary therapy and therapeutic diets. You’ll gain the confidence in identifying supporting evidence for clinical practice and will focus on nutritional management of common diseases, such as cardiovascular disease, type 2 diabetes, gastrointestinal disorders, and renal/liver disease. In addition to lectures, you’ll have the opportunity to put your problem-solving skills to the test with hands-on interactive practical laboratory experience. Put your knowledge into action within the real world by exploring the potential application of various methodologies as part of your coursework.

Our understanding of the genome is constantly growing. In this module, you’ll be introduced to the fundamental elements of genomics, human genetics and genetic variation. You’ll explore genetics in connection to disease and how genomic medicine can be utilised in relation to disease mechanisms. You’ll get the chance to investigate the effects of gene mutations and variations in DNA sequences (gene polymorphisms) in human health, with an opportunity to join in on an in-depth discussion on linkage. In addition, you’ll learn all about personalised medicine and the role of a key enzyme in the liver (cytochrome P450) in the metabolism of drugs and toxicity.

Investigating DNA and molecular concepts has never been so encapsulating. Learn about the structure and function of prokaryotic and eukaryotic genomes alongside top scientists in the field, helping to address the world’s biggest challenges. Secure knowledge on the latest experimental evidence supporting cutting-edge concepts and laboratory techniques.

You’ll gain a solid insight into the most up-to-date biomedical applications and modern molecular tools used to implement recombinant DNA techniques and DNA sequencing, complementing the Genetics Module. Your learning journey will be supported into the Biomedical Science and Medical Science employability routes, for which there is a growing demand, and you’ll be thoroughly guided by leading specialists on making successful job applications for those who embark on placement work experience.

Immerse yourself in the most exciting research and developmental topics surrounding microscopic cell biology and bio-imaging analysis. In this module, you'll gain an in-depth insight and appreciation of the molecular mechanisms at play in the cell biology of mammals, yeast and plants. You’ll investigate some of the techniques underpinning the latest associated research in the field, and dive into an exploration of fundamental biological processes in topics such as cell signalling and interacting proteins, the endomembrane system, and the cell cycle. Innovative advanced experimental bio-imaging has opened up new avenues to implement highly powerful experimental methods for investigation of cell biology. Light microscopy techniques will allow you to probe important biological questions, observe living cells of animals and plants, and measure intracellular processes including protein interactions in different biological situations.

In this module, you’ll gain an insight into a full range of pathological processes, and their effects on the human body. In particular, you’ll be focusing on the pathogenesis, pathology and pathophysiology of common cardio-pulmonary disease conditions including obstructive and restrictive lung disease, heart failure and obstructive sleep apnoea. You’ll learn how to make meaningful connections between physiological principles and pathophysiological mechanisms. Furthermore, you’ll gain confidence in your abilities to problem solve with the opportunity to get hands-on with cutting-edge and controversial issues in the field through a combination of problem-based learning, case studies, student debates, hospital visits and guest lectures by medical and healthcare professionals within the field.

You'll learn about major theoretical and technological advances in Genetics and Genomics, and their significance in addressing challenges in biological and medical research. You’ll focus on the variation of population history, selection inference, and analysing variation in complex traits. You’ll also explore the use of comparative genomics and the evolutionary relatedness among groups of organisms (phylogenetics) to make connections between evolutionary relationships, and investigate genome evolution.

Your learning journey will encompass microbiomes in human health and ecosystems, and the study of gene function. You’ll get hands on with key techniques such as retrieval of data from public resources, population statistics, genome-wide association studies, gene annotation, transcriptome analysis, transcription factor binding prediction and characterisation of epigenetic modifications. You’ll devise a research programme addressing a current challenge in biological and medical science.

This is a great addition to your CV and helps you to stand out from the crowd when looking for a graduate job.

You can sign up for work experience in your first year and you’ll complete the work experience preparation module in Year 2. You'll be supported with your search for work experience and develop techniques and skills useful at interviews and assessment centres. Additional support is also available from dedicated work experience staff members. During your work experience you will receive regular support from your own Work Experience Tutor.

Your work experience must be full time and be for a minimum number of weeks. The salary must be commensurate with the role and not less than the minimum wage for the country in which the placement is taking place.

We have a number of links with local and regional employers including the NHS and local NGOs/Charities that can support you in your search for relevant work experience.

You'll have the opportunity to choose a topic that is relevant to your programme. Building upon your knowledge from your previous year of study, for those on the MBiol programme, you'll get the chance to immerse yourself in the production of a detailed project plan for your Masters year project/dissertation. For all other study programmes, you’ll pick a project in agreement with your supervisor, which will be submitted for approval by end of week 1 in the semester in which the study is to be undertaken. You’ll start planning your work six weeks before the start of the semester to give you ample time for submission. You’ll have access to Moodle where you’ll be able to view your module learning contract template and find all the information you need to successfully complete your independent study.

The module is a period of research practice in a professional working environment. The objective is to augment and develop the skills and competencies delivered by the degree programme, and to practice science in a working context. The period of research practice will allow the student to apply the knowledge and learning gained in their academic training while carrying out their own supervised research in an active research environment. The research will be related to, and draw on, the theoretical knowledge and skills already acquired during the first three years of their degree programme. It is expected that the student will gain scientific and interpersonal skills which complement the learning experience delivered by taught modules. The research practiced carried out as a team member within an active research environment will therefore contribute to the training of talented students interested in careers as practising scientists.

Our understanding of basic concepts in molecular biology has given rise to the different ‘omics’ areas of modern research and application (genomics, transcriptomics, proteomics, metabolomics etc.). This module will begin by refreshing your understanding of topics such as DNA structure, replication, mutation and repair, and gene expression. We will also explore how the biological concepts have been exploited by scientists to derive and apply the wide array of methodologies that have come to be known collectively by the term “molecular biology”, such as DNA cloning, PCR, quantitative PCR, microarrays and RNA interference. This expanding collection of technologies provides scientists with a fundamental basis for studying biological processes and various aspects of human disease. You'll use several of these techniques, through laboratory-based practical work, to deepen your understanding and illustrate potential applications.

he independent study is a module that provides students with an opportunity to address a discipline area is not formally offered as part of the taught programme or the student has a desire to expand on a topic area that was superficially covered. In this module we encourage students to create a product output that is potentially useful for the industry of interest. The type of product though is chosen within consultation with the module leader and their chosen supervisor for the activity. There are no formal teaching components for this course but instead students are expected to conduct the work independently with some supervisory/stakeholder guidance. The module requires a learning contract which is agreed between the student and a supervising member of staff in the semester prior to the one in which the study is to be undertaken, and this must be approved by the Subject Examination Committee. Only once the learning contract has been formally approved will the module be registered on the student's programme of study.

This module aims to consider the cutting-edge genomic technologies now being used in clinical settings and we hope to include a hospital genetics lab hospital tour. Topics explored will include methods in medical genetics and the application of molecular and genetic tools to the use of information banks such as Personal Genomes and Big Data, and we will look at the role of collaborations such as Genomics England in the expansion of genomic information. The module will also introduce the application of genomic data to the development of biomarker diagnosis, personalised medicine, patient surrogate treatment models, self-monitoring and infectious disease evolution.

The module examines the current trends in high-throughput genome sequencing methods, strategies for sequence assembly and the use of such data for phylogeny analysis and gene taxonomy. The relationship between genome structure and protein function will be studied in detail through the use of a wide range of bioinformatics tools, with a focus genome analysis in health and disease. The practical element of this module consists of weekly bioinformatics workshops that introduce key tools in genome science and that will be important in other modules and in your research project.

In this module, you’ll immerse yourself within the realms of genetic and population genetic concepts that form the basis of genome analysis. You’ll get involved in computing practical lessons using a series of bioinformatics tools, widening your knowledge of the programming languages and software platforms that are used in genomic research today. If you’re ready to tackle the interpretation of biological data and apply them in the design of experiments to form the basis for biological research, then this module is for you. Bioinformatics careers will take you into forensics, environmental, agricultural, pharmaceutical, and biotechnology-related sectors.

This module offers the opportunity to study how genetic and genomic technologies can be used to identify, characterise and diagnose diseases in three subject areas: molecular oncology, chronic and congenital diseases and infectious disease. Clinical case studies and research seminars will introduce current topics in the field allowing you to identify topics that particularly interest you, for further independent reading. You will learn to critically explore concepts and subject areas through journal clubs and discussion sessions leading to a final essay assessment. You will learn skills such as the integration of information from various sources across subject areas, the application of understanding in an analytical setting, the individual exploration of a chosen subject area and the critical analysis of research material.